Lunes, Mayo 28, 2018

What does Glutathione do in our bodies?



Antioxidant - GSH is the body’s master Antioxidant, our bodies depend on GSH for the removal of toxins and GSH is at the heart of all immune functions. Other antioxidants in our body depend on GSH to function properly.

Detoxification - GSH detoxifies a large number of pollutants by binding to carcinogens, heavy metals, herbicides, pesticides and radiation by forming a soluble compound with the toxin that can then be excreted through the urine or bile.

Immune system - Healthy growth and activity of immune cells depends on the availability of GSH. The protective activity of GSH is two-fold – it enhances the activity of immune cells and also functions as an antioxidant within them.

Increased Energy - Our energy levels are a result of many factors - everything from the biochemical reactions taking place within our cells, to muscle function and even your sense of well-being. GSH enables the mitochondria of a cell to remain fully charged, enhancing muscle strength and endurance. Clinical trials have shown that lowering GSH in the mitochondria results in cell death.

Repair - Our body is constantly under attack from free radicals, some from external sources and some generated in our own body. Free radicals attack the nearest stable molecule, "stealing" its electron. A molecule that loses an electron then becomes a free radical itself and attacks the next nearest stable molecule, this begins a chain reaction. Once the reaction is started it can cascade through hundreds of molecules. As this occurs over and over again the cell eventually dies or mutates. Sometimes the mutated cell mutates to a point that we know as cancer. GSH performs a vital role in repairing the damaged DNA by replacing the missing electron. Normal to elevated GSH keeps the repair of our cells at a maximum and reduces the number of cell mutations that would occur otherwise.

GSH is at the heart of all immune functions and low GSH levels are seen in many diseases such as AIDS, advanced diabetes, and cancers. Raising and maintaining GSH levels can help minimize the risk of diseases.

Glutathione exists in reduced (GSH) and oxidized (GSSG) states. In healthy cells and tissue, more than 90% of the total Glutathione is in the reduced form (GSH) and less than 10% exists in the oxidized form (GSSG).

An increased GSSG-to-GSH ratio is considered indicative of oxidative stress. The ratio of reduced Glutathione to oxidized Glutathione within cells is often used scientifically as a measure of cellular toxicity.

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